DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Dihydrofolate reductase
Ligand Name
3'-[(2R)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OKJCHFXBCVXSIZ-AWEZNQCLSA-N
SMILES
CCc1c(c(nc(n1)N)N)C#CC(C)c2cc(cc(c2)OC)c3ccc(cc3)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6DDP
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Color Legend
Unassigned regionsLigand / hetero atomse6ddpA1e6ddpB1e6ddpC1e6ddpD1
ECOD domains from experimental PDB structures interacting with ligand G6Y
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P9WNX1n/aG6Y6ddpe6ddpA1A:1-159
P9WNX1n/aG6Y6ddpe6ddpB1B:1-159
P9WNX1n/aG6Y6ddpe6ddpC1C:1-159
P9WNX1n/aG6Y6ddpe6ddpD1D:1-159