DrugDomain logoDrugDomain

2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID

P9WNX1 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00642

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB00642

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P9WNX1DB006426nncLYAA203e6nncA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P9WNX1DB006426nncLYAB203e6nncB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1