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Attributes

UniProt ID
P9WNX1
Protein Name
Dihydrofolate reductase
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 6DDP
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Color Legend
Unassigned regionsLigand / hetero atomse6ddpA1e6ddpB1e6ddpC1e6ddpD1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P9WNX1DB02338NDP6ddpe6ddpA1A:1-159
P9WNX1DB02338NDP6ddpe6ddpB1B:1-159
P9WNX1DB02338NDP6ddpe6ddpC1C:1-159
P9WNX1DB02338NDP6ddpe6ddpD1D:1-159
P9WNX1DB02338NDP6ddse6ddsA1A:1-159
P9WNX1DB02338NDP6ddse6ddsB1B:1-159
P9WNX1DB02338NDP6ddse6ddsC1C:1-159
P9WNX1DB02338NDP6ddse6ddsD1D:1-159
P9WNX1DB02338NDP6ddwe6ddwA1A:1-159
P9WNX1DB02338NDP6nnce6nncA1A:1-159
P9WNX1DB02338NDP6nnce6nncB1B:1-159
P9WNX1DB02338NDP6nnde6nndA1A:1-159
P9WNX1DB02338NDP6nnde6nndB1B:1-159
P9WNX1DB02338NDP6nnhe6nnhA1A:1-159
P9WNX1DB02338NDP6nnhe6nnhB1B:1-159
P9WNX1DB02338NDP6nnie6nniA1A:1-159
P9WNX1DB02338NDP6nnie6nniB1B:1-159