Attributes
UniProt ID
Protein Name
E3 ubiquitin-protein ligase Mdm2
Ligand Name
4-({6-[(6-chloro-3-{1-[(4-chlorophenyl)methyl]-4-(4-fluorophenyl)-1H-imidazol-5-yl}-1H-indole-2-carbonyl)oxy]hexyl}amino)-4-oxobutanoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
MEJMFPQUMDEAQP-UHFFFAOYSA-N
SMILES
c1cc(ccc1Cn2cnc(c2c3c4ccc(cc4[nH]c3C(=O)OCCCCCCNC(=O)CCC(=O)O)Cl)c5ccc(cc5)F)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 5J7F
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Color Legend
Unassigned regionsLigand / hetero atomse5j7fA1e5j7fB1e5j7fC1e5j7fD1
ECOD domains from experimental PDB structures interacting with ligand 6GG
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q00987 | n/a | 6GG | 5j7f | e5j7fA1 | A:11-111 |
| Q00987 | n/a | 6GG | 5j7f | e5j7fB1 | B:12-114 |
| Q00987 | n/a | 6GG | 5j7f | e5j7fC1 | C:11-111 |
| Q00987 | n/a | 6GG | 5j7f | e5j7fD1 | D:12-110 |
| Q00987 | n/a | 6GG | 5j7g | e5j7gA1 | A:17-110 |
| Q00987 | n/a | 6GG | 5j7g | e5j7gB1 | B:17-114 |
| Q00987 | n/a | 6GG | 5j7g | e5j7gC1 | C:17-111 |
| Q00987 | n/a | 6GG | 5j7g | e5j7gD1 | D:17-111 |