DrugDomain logoDrugDomain

1-[[(1~{R})-2-[(5-chloranylpyridin-2-yl)methyl]-1-(4-chlorophenyl)-7-fluoranyl-3-oxidanylidene-5-(2-oxidanylpropan-2-yl)isoindol-1-yl]oxymethyl]cyclopropane-1-carboxamide

Q00987 — E3 ubiquitin-protein ligase Mdm2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TUZ

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TUZ

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q00987n/a7birTUZA203e7birA1SWIB/MDM2 domainSWIB/MDM2 domainSWIB/MDM2 domainSWIB