Attributes
UniProt ID
Protein Name
Dual specificity mitogen-activated protein kinase kinase 1
Ligand Name
5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
RFWVETIZUQEJEF-UHFFFAOYSA-N
SMILES
c1cc(c(cc1I)F)Nc2c(ccc3n2cnc3)C(=O)NOCCO
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6NYB
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Color Legend
Unassigned regionsLigand / hetero atomse6nybA1e6nybA2e6nybB1e6nybC1e6nybD1
ECOD domains from experimental PDB structures interacting with ligand DB11982
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q02750 | DB11982 | LCJ | 6nyb | e6nybB1 | B:56-267,B:307-383 |
| Q02750 | DB11982 | LCJ | 6pp9 | e6pp9B1 | B:38-274,B:307-383 |
| Q02750 | DB11982 | LCJ | 6q0j | e6q0jC1 | C:43-274,C:306-379 |
| Q02750 | DB11982 | LCJ | 6q0j | e6q0jD1 | D:43-274,D:306-379 |
| Q02750 | DB11982 | LCJ | 6q0t | e6q0tC1 | C:43-274,C:306-379 |
| Q02750 | DB11982 | LCJ | 8dgs | e8dgsB1 | B:38-274,B:307-383 |
| Q02750 | DB11982 | LCJ | 8dgt | e8dgtB1 | B:43-274,B:307-385 |