DAUNOMYCIN

Q02880 — DNA topoisomerase 2-beta

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00694

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
Q02880	DB00694	DM1	nD1	225.1.1	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HATPase_c
Q02880	DB00694	DM1	nD2	212.1.1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	DNA_gyraseB
Q02880	DB00694	DM1	nD3	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	Toprim,TOPRIM_C
Q02880	DB00694	DM1	nD4	101.1.2	HTH	HTH	winged helix domain	DNA_topoisoIV
Q02880	DB00694	DM1	nD5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV

Show other predicted domains (84)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
3QX3	e3qx3A1	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e3qx3B6	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e3qx3A11	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e3qx3B8	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e3qx3A12	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e3qx3B7	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e3qx3A13	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e3qx3B5	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
4G0U	e4g0uA4	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4g0uB14	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4g0uA1	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4g0uB16	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4g0uB15	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0uA5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0uB13	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0uA6	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
4G0V	e4g0vA4	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4g0vB14	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4g0vA1	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4g0vB16	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4g0vB15	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0vA5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0vB13	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0vA6	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
4G0W	e4g0wA4	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4g0wB10	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4g0wA1	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4g0wB12	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4g0wB11	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0wA5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0wB9	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e4g0wA6	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
4J3N	e4j3nB10	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4j3nA10	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e4j3nB12	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4j3nA9	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e4j3nB11	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4j3nA11	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e4j3nB9	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e4j3nA12	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
5GWI	e5gwiA3	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5gwiB3	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5gwiA2	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5gwiB4	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5gwiA1	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwiB2	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwiA4	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwiB1	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
5GWJ	e5gwjA2	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5gwjB4	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5gwjA1	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5gwjB3	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5gwjA3	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwjB2	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwjA4	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e5gwjB1	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
5ZAD	e5zadA1	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5zadB1	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5zadA3	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5zadB2	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5zadA2	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e5zadB5	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e5zadA5	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zadB4	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zadA4	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zadB3	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
5ZEN	e5zenA1	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5zenA4	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5zenA5	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e5zenA2	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zenA3	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
5ZQF	e5zqfA3	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5zqfA5	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5zqfA2	4012.1.1	SSHS domain	SSHS domain in type II DNA topoisomerase	SSHS domain in type II DNA topoisomerase	TOPRIM_C
	e5zqfA1	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zqfA4	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
5ZRF	e5zrfB3	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5zrfA3	101.1.2	HTH	HTH	winged helix domain	HTH_1
	e5zrfB1	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5zrfA2	2006.1.3	HAD domain-like	HAD domain-related	Toprim domain	DNA_gyraseB_C,Toprim
	e5zrfB2	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zrfA1	4014.1.1	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	a+b domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zrfB4	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV
	e5zrfA4	4016.1.1	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	alpha-helical domain in type II DNA topoisomerase	DNA_topoisoIV

ECOD domains from experimental PDB structures interacting with ligand DB00694

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found