Attributes
UniProt ID
Protein Name
DNA topoisomerase 2-beta
Ligand Name
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VJJPUSNTGOMMGY-MRVIYFEKSA-N
SMILES
CC1OCC2C(O1)C(C(C(O2)OC3c4cc5c(cc4C(C6C3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 3QX3
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Color Legend
Unassigned regionsLigand / hetero atomse3qx3A1e3qx3A11e3qx3A12e3qx3A13e3qx3B5e3qx3B6e3qx3B7e3qx3B8
ECOD domains from experimental PDB structures interacting with ligand DB00773
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q02880 | DB00773 | EVP | 3qx3 | e3qx3A1 | A:733-861 |
| Q02880 | DB00773 | EVP | 3qx3 | e3qx3A11 | A:452-591,A:638-732 |
| Q02880 | DB00773 | EVP | 3qx3 | e3qx3B6 | B:691-841 |
| Q02880 | DB00773 | EVP | 3qx3 | e3qx3B8 | B:449-592,B:637-690 |
| Q02880 | DB00773 | EVP | 5zrf | e5zrfA2 | A:452-591,A:638-732 |
| Q02880 | DB00773 | EVP | 5zrf | e5zrfA3 | A:733-861 |
| Q02880 | DB00773 | EVP | 5zrf | e5zrfB1 | B:449-592,B:637-690 |
| Q02880 | DB00773 | EVP | 5zrf | e5zrfB3 | B:691-841 |