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Attributes

UniProt ID
Protein Name
DNA topoisomerase 2-beta
Ligand Name
chloro{4,5-di(amino-kappaN)-N-[9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl]pentanamide}platinum
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UVMRTXMJNLJFNR-JLXFAVSYSA-M
SMILES
COc1cc(cc(c1O)OC)C2c3cc4c(cc3C(C5C2C(=O)OC5)NC(=O)CCC6C[NH2][Pt]([NH2]6)Cl)OCO4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 5GWJ
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Color Legend
Unassigned regionsLigand / hetero atomse5gwjA1e5gwjA2e5gwjA3e5gwjA4e5gwjB1e5gwjB2e5gwjB3e5gwjB4
ECOD domains from experimental PDB structures interacting with ligand N2W
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q02880n/aN2W5gwje5gwjA1A:452-591,A:638-732
Q02880n/aN2W5gwje5gwjA2A:733-861
Q02880n/aN2W5gwje5gwjB3B:449-592,B:637-690
Q02880n/aN2W5gwje5gwjB4B:691-841