[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate

Q05397 — Focal adhesion kinase 1

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12010

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
Q05397	DB12010	2RC	nD2	197.1.1	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	FERM_M
Q05397	DB12010	2RC	nD4	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
Q05397	DB12010	2RC	nD5	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT

Show other predicted domains (58)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1K04	e1k04A1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
1K05	e1k05A1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1k05B1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1k05C1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
1MP8	e1mp8A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
1OW6	e1ow6A1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1ow6B1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1ow6C1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
1OW7	e1ow7A1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1ow7B1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1ow7C1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
1OW8	e1ow8A1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1ow8B1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e1ow8C1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
2ETM	e2etmA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2ETM	e2etmB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2IJM	e2ijmA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2IJM	e2ijmB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3B71	e3b71A1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e3b71B1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e3b71C1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
3BZ3	e3bz3A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3PXK	e3pxkA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3PXK	e3pxkB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3S9O	e3s9oA1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e3s9oC1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
	e3s9oB1	601.16.1	Four-helical up-and-down bundle	FAT domain of focal adhesion kinase	FAT domain of focal adhesion kinase	Focal_AT
4EBV	e4ebvA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4EBW	e4ebwA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4GU6	e4gu6A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4GU6	e4gu6B1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4GU9	e4gu9A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4GU9	e4gu9B1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4I4E	e4i4eA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4I4F	e4i4fA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4K8A	e4k8aA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4K8A	e4k8aB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4K9Y	e4k9yA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4KAB	e4kabA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4KAB	e4kabB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4KAO	e4kaoA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4KAO	e4kaoB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4NY0	e4ny0D3	197.1.1	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	FERM_M
	e4ny0A3	197.1.1	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	FERM_M
	e4ny0B3	197.1.1	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	FERM_M
	e4ny0C3	197.1.1	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	Acyl-CoA binding protein-like	FERM_M
	e4ny0D2	220.1.1	PH domain-like	PH domain-like	PH domain-like	PH
	e4ny0A2	220.1.1	PH domain-like	PH domain-like	PH domain-like	PH
	e4ny0B2	220.1.1	PH domain-like	PH domain-like	PH domain-like	PH
	e4ny0C2	220.1.1	PH domain-like	PH domain-like	PH domain-like	PH
	e4ny0D1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e4ny0A1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e4ny0B1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e4ny0C1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
4Q9S	e4q9sA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6I8Z	e6i8zA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6LES	e6lesY2	7523.1.1	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Periplasmic binding protein-like II	HisG
6LES	e6lesB1	7523.1.1	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Periplasmic binding protein-like II	HisG

ECOD domains from experimental PDB structures interacting with ligand DB12010

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found