Attributes
UniProt ID
Protein Name
Tyrosine-protein phosphatase non-receptor type 11
Ligand Name
6-[4-(aminomethyl)-4-methyl-piperidin-1-yl]-3-[2,3-bis(chloranyl)phenyl]sulfanyl-pyrazin-2-amine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
HFZSVNQUAOVFHI-UHFFFAOYSA-N
SMILES
CC1(CCN(CC1)c2cnc(c(n2)N)Sc3cccc(c3Cl)Cl)CN
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 7VXG
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse7vxgA1e7vxgA2e7vxgA3e7vxgB1e7vxgB2e7vxgB3e7vxgC1e7vxgC2e7vxgC3e7vxgD1e7vxgD2e7vxgD3
ECOD domains from experimental PDB structures interacting with ligand 83Q
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q06124 | n/a | 83Q | 7vxg | e7vxgA1 | A:109-216 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgA2 | A:3-108 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgA3 | A:217-525 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgB1 | B:110-218 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgB2 | B:4-110 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgB3 | B:219-525 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgC1 | C:109-216 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgC2 | C:3-108 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgC3 | C:217-525 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgD1 | D:109-216 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgD2 | D:3-108 |
| Q06124 | n/a | 83Q | 7vxg | e7vxgD3 | D:217-525 |