(1~{S})-1'-[5-[2-(trifluoromethyl)pyridin-3-yl]sulfanyl-3~{H}-imidazo[4,5-b]pyrazin-2-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine
Q06124 — Tyrosine-protein phosphatase non-receptor type 11
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand P8O
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand P8O
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q06124 | n/a | 8b5y | P8O | A | 601 | e8b5yA1 | Flavodoxin-like | Flavoproteins/Phosphotyrosine protein phosphatases-like | (Phosphotyrosine protein) phosphatases II | Y_phosphatase |
| Q06124 | n/a | 8b5y | P8O | A | 601 | e8b5yA2 | SH2 | SH2 | SH2 | SH2 |
| Q06124 | n/a | 8b5y | P8O | A | 601 | e8b5yA3 | SH2 | SH2 | SH2 | SH2 |
| Q06124 | n/a | 8b5y | P8O | B | 601 | e8b5yB1 | SH2 | SH2 | SH2 | SH2 |
| Q06124 | n/a | 8b5y | P8O | B | 601 | e8b5yB2 | SH2 | SH2 | SH2 | SH2 |
| Q06124 | n/a | 8b5y | P8O | B | 601 | e8b5yB3 | Flavodoxin-like | Flavoproteins/Phosphotyrosine protein phosphatases-like | (Phosphotyrosine protein) phosphatases II | Y_phosphatase |