DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase BTK
Ligand Name
4-[8-azanyl-3-[(2~{S})-1-[4-(dimethylamino)butanoyl]pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-(1,3-thiazol-2-yl)benzamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
HUXVNVAKNWKLJM-IBGZPJMESA-N
SMILES
CN(C)CCCC(=O)N1CCCC1c2nc(c3n2ccnc3N)c4ccc(cc4)C(=O)Nc5nccs5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5FBN
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Color Legend
Unassigned regionsLigand / hetero atomse5fbnC1e5fbnD1
ECOD domains from experimental PDB structures interacting with ligand 5WE
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q06187n/a5WE5fbne5fbnC1C:395-658
Q06187n/a5WE5fbne5fbnD1D:394-658
Q06187n/a5WE5fboe5fboA1A:392-659
Q06187n/a5WE6x3ne6x3nA1A:392-659
Q06187n/a5WE6x3oe6x3oA1A:395-659
Q06187n/a5WE6x3oe6x3oB1B:393-659