DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
2-Amino-5-(1-naphthylsulfanyl)-3,9-dihydro-4H-pyrimido[4,5-b]indol-4-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NSASWBYEPOLHJW-UHFFFAOYSA-N
SMILES
c1ccc2c(c1)cccc2Sc3cccc4c3c5c([nH]4)N=C(NC5=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4KYA
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Color Legend
Unassigned regionsLigand / hetero atomse4kyaA2e4kyaA3e4kyaB1e4kyaB2e4kyaC1e4kyaC2e4kyaD1e4kyaD2e4kyaE1e4kyaE2e4kyaF1e4kyaF2e4kyaG2e4kyaG3e4kyaH2e4kyaH3
ECOD domains from experimental PDB structures interacting with ligand 1UG
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q07422n/a1UG4kyae4kyaA3A:285-610
Q07422n/a1UG4kyae4kyaB1B:285-610
Q07422n/a1UG4kyae4kyaC1C:285-610
Q07422n/a1UG4kyae4kyaD1D:285-610
Q07422n/a1UG4kyae4kyaE1E:285-610
Q07422n/a1UG4kyae4kyaF1F:285-610
Q07422n/a1UG4kyae4kyaG3G:285-610
Q07422n/a1UG4kyae4kyaH2H:285-610