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5-(3-chlorophenyl)-6-[2-(3-phenoxypropoxy)ethyl]pyrimidine-2,4-diamine

Q07422 Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 4TS

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 4TS

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q07422n/a7fgy4TSA702e7fgyA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a7fgy4TSB702e7fgyB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a7fgy4TSC702e7fgyC1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a7fgy4TSD702e7fgyD1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1