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5-[4-(3,4-dichlorophenyl)piperazin-1-yl]pyrimidine-2,4-diamine

Q07422 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 73X

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 73X

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q07422n/a5t0l73XA704e5t0lA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a5t0l73XB704e5t0lB2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1