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5-{4-[3-(2-methoxypyrimidin-5-yl)phenyl]piperazin-1-yl}pyrimidine-2,4-diamine

Q07422 Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand BOD

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand BOD

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q07422n/a6aohBODA704e6aohA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a6aohBODB704e6aohB2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a6n1tBODA704e6n1tA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q07422n/a6n1tBODB704e6n1tB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1