DrugDomain logoDrugDomain

Attributes

UniProt ID
Q07422
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
DrugBank ID
DB03541
PDB Ligand Accession
CB3
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LTKHPMDRMUCUEB-IBGZPJMESA-N
SMILES
C#CCN(Cc1ccc2c(c1)C(=O)N=C(N2)N)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 4ECK
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Color Legend
Unassigned regionsLigand / hetero atomse4eckA2e4eckA3e4eckB2e4eckB3
ECOD domains from experimental PDB structures interacting with ligand DB03541
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q07422DB03541CB34ecke4eckA3A:285-610
Q07422DB03541CB34ecke4eckB3B:285-610
Q07422DB03541CB34eile4eilA2A:285-610
Q07422DB03541CB34eile4eilB3B:285-610
Q07422DB03541CB34eile4eilC1C:285-610
Q07422DB03541CB34eile4eilD1D:285-610
Q07422DB03541CB34eile4eilE1E:285-610
Q07422DB03541CB34eile4eilF2F:285-610
Q07422DB03541CB34eile4eilG2G:285-610
Q07422DB03541CB34eile4eilH1H:285-610
Q07422DB03541CB35t0le5t0lA2A:287-610
Q07422DB03541CB35t0le5t0lB1B:285-610
Q07422DB03541CB36aoge6aogA2A:285-610
Q07422DB03541CB36aoge6aogB2B:285-610
Q07422DB03541CB36aohe6aohA1A:285-610
Q07422DB03541CB36aohe6aohB1B:285-610
Q07422DB03541CB36aoie6aoiA2A:285-610
Q07422DB03541CB36aoie6aoiB1B:285-610
Q07422DB03541CB36n1se6n1sA2A:285-610
Q07422DB03541CB36n1se6n1sB1B:285-610
Q07422DB03541CB36n1te6n1tA1A:285-610
Q07422DB03541CB36n1te6n1tB2B:285-610