Attributes
UniProt ID
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
WKSAUQYGYAYLPV-UHFFFAOYSA-N
SMILES
CCc1c(c(nc(n1)N)N)c2ccc(cc2)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6AOG
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Color Legend
Unassigned regionsLigand / hetero atomse6aogA1e6aogA2e6aogB1e6aogB2
ECOD domains from experimental PDB structures interacting with ligand DB00205
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q07422 | DB00205 | CP6 | 6aog | e6aogA1 | A:3-252 |
| Q07422 | DB00205 | CP6 | 6aog | e6aogB1 | B:4-252 |
| Q07422 | DB00205 | CP6 | 7fgw | e7fgwA2 | A:1-48,A:74-200,A:220-257 |
| Q07422 | DB00205 | CP6 | 7fgw | e7fgwB2 | B:2-48,B:74-200,B:220-256 |
| Q07422 | DB00205 | CP6 | 7fgw | e7fgwC2 | C:2-48,C:74-200,C:220-254 |
| Q07422 | DB00205 | CP6 | 7fgw | e7fgwD1 | D:1-48,D:74-200,D:220-258 |