DrugDomain logoDrugDomain

Attributes

UniProt ID
Q07422
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
FOLIC ACID
DrugBank ID
DB00158
PDB Ligand Accession
FOL
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OVBPIULPVIDEAO-LBPRGKRZSA-N
SMILES
c1cc(ccc1C(=O)NC(CCC(=O)O)C(=O)O)NCc2cnc3c(n2)C(=O)N=C(N3)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 4ECK
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Color Legend
Unassigned regionsLigand / hetero atomse4eckA2e4eckA3e4eckB2e4eckB3
ECOD domains from experimental PDB structures interacting with ligand DB00158
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q07422DB00158FOL4ecke4eckA2A:3-44,A:74-193,A:226-251
Q07422DB00158FOL4ecke4eckB2B:3-44,B:74-193,B:226-251
Q07422DB00158FOL4eile4eilA3A:4-252
Q07422DB00158FOL4eile4eilB2B:3-251
Q07422DB00158FOL4eile4eilC5C:4-252
Q07422DB00158FOL4eile4eilD2D:3-251
Q07422DB00158FOL4eile4eilE5E:4-252
Q07422DB00158FOL4eile4eilF3F:3-251
Q07422DB00158FOL4eile4eilG5G:4-252
Q07422DB00158FOL4eile4eilH2H:3-251
Q07422DB00158FOL4kyae4kyaA2A:4-252
Q07422DB00158FOL4kyae4kyaB2B:3-251
Q07422DB00158FOL4kyae4kyaC2C:4-252
Q07422DB00158FOL4kyae4kyaD2D:3-251
Q07422DB00158FOL4kyae4kyaE2E:4-252
Q07422DB00158FOL4kyae4kyaF2F:3-251
Q07422DB00158FOL4kyae4kyaG2G:4-252
Q07422DB00158FOL4kyae4kyaH3H:3-251