2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Q08210 — Dihydroorotate dehydrogenase , mitochondrial
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB12397
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB12397
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q08210 | DB12397 | 4rx0 | D65 | A | 1001 | e4rx0A1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | DHO_dh |
| Q08210 | DB12397 | 5boo | D65 | A | 1001 | e5booA1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | DHO_dh |
| Q08210 | DB12397 | 5boo | D65 | B | 1001 | e5booB1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | DHO_dh |