DrugDomain logoDrugDomain

[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate

Q08881 — Tyrosine-protein kinase ITK/TSK

← Back

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12010

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
Q08881DB120102RCnD2398.1.1Btk/CHORD zinc fingersBtk/CHORD zinc fingersBtk/CHORD zinc fingersn/a
Q08881DB120102RCnD5206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
Show other predicted domains (59)
PDB IDDomain NameECOD IDX GroupH GroupT GroupF Group
1SM2e1sm2A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e1sm2B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1SNUe1snuB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e1snuA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
1SNXe1snxA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e1snxB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
2E6Ie2e6iA1398.1.1Btk/CHORD zinc fingersBtk/CHORD zinc fingersBtk/CHORD zinc fingersBTK
2LMJe2lmjA14.1.1SH3SH3SH3SH3_1
2YUQe2yuqA14.1.1SH3SH3SH3SH3_1
3MIYe3miyA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3miyB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3MJ1e3mj1A2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3MJ2e3mj2A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3QGWe3qgwA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3qgwB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3QGYe3qgyA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3qgyB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3T9Te3t9tA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3V5Je3v5jA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3v5jB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3V5Le3v5lC1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3v5lD1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3v5lA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3v5lB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3V8Te3v8tB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3v8tA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3V8We3v8wA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3v8wB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4HCTe4hctA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4HCUe4hcuA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4HCVe4hcvA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4KIOe4kioC1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4kioA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4kioB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4kioD1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4L7Se4l7sA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4l7sB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4M0Ye4m0yA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4M0Ze4m0zA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4M12e4m12A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4M13e4m13A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4M14e4m14A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4M15e4m15A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4MF0e4mf0A2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4mf0B2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4MF1e4mf1A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4mf1B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4PP9e4pp9A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4pp9B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4PPAe4ppaA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ppaB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4PPBe4ppbA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ppbB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4PPCe4ppcA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ppcB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4PQNe4pqnA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4QD6e4qd6A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4qd6B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4RFMe4rfmA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase

ECOD domains from experimental PDB structures interacting with ligand DB12010

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
No experimental ECOD data found