DrugDomain logoDrugDomain

1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine

Q12809 — Voltage-gated inwardly rectifying potassium channel KCNH2

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Attributes

UniProt ID
Q12809
Protein Name
Voltage-gated inwardly rectifying potassium channel KCNH2
Ligand Name
1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine
DrugBank ID
DB00637
PDB Ligand Accession
XB7
ChEMBL ID
CHEMBL296419
PubChem ID
2247
InChIKey
GXDALQBWZGODGZ-UHFFFAOYSA-N
SMILES
COc1ccc(cc1)CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(cc5)F
Drug Action
inhibitor
Affinity Metrics
ki:2.9 nM
ic50:0.9 nM
ec50:1.9 nM