1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine

Q12809 — Voltage-gated inwardly rectifying potassium channel KCNH2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00637

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
Q12809	DB00637	XB7	nD1	223.1.1	Profilin-like	sensor domains	sensor domains	PAS_9
Q12809	DB00637	XB7	nD2	10.12.1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	cNMP_binding, Ion_trans, Ion_trans_2

Show other predicted domains (16)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1BYW	e1bywA1	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
2L0W	e2l0wA1	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
2L1M	e2l1mA1	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
2L4R	e2l4rA1	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
2N7G	e2n7gA1	10.12.1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	cNMP_binding
4HP9	e4hp9A1	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
4HQA	e4hqaA2	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
5VA1	e5va1A1	10.12.1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	cNMP_binding
	e5va1A2	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
	e5va1A3	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
5VA2	e5va2A1	10.12.1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	cNMP_binding
	e5va2A2	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
	e5va2A3	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
5VA3	e5va3A1	10.12.1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	cNMP_binding
	e5va3A2	223.1.1	Profilin-like	sensor domains	sensor domains	PHY
	e5va3A3	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan

ECOD domains from experimental PDB structures interacting with ligand DB00637

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found