2-(2-{4-[(6-aminopyridin-3-yl)sulfonyl]piperazin-1-yl}-3,3'-bipyridin-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol
Q14397 — Glucokinase regulatory protein
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 2TO
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 2TO
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q14397 | n/a | 4olh | 2TO | A | 701 | e4olhA1 | RuvA-C | C-terminal lid domain of glucokinase regulatory protein | C-terminal lid domain of glucokinase regulatory protein | GKRP-like_C |
| Q14397 | n/a | 4olh | 2TO | A | 701 | e4olhA2 | Flavodoxin-like | Ribosomal protein S2/SIS domain | Ribosomal protein S2/SIS domain | GKRP_SIS_N |
| Q14397 | n/a | 4olh | 2TO | B | 701 | e4olhB2 | Flavodoxin-like | Ribosomal protein S2/SIS domain | Ribosomal protein S2/SIS domain | GKRP_SIS_N |
| Q14397 | n/a | 4olh | 2TO | B | 701 | e4olhB3 | RuvA-C | C-terminal lid domain of glucokinase regulatory protein | C-terminal lid domain of glucokinase regulatory protein | GKRP-like_C |