DrugDomain

Attributes

UniProt ID

Q14416

Protein Name

Metabotropic glutamate receptor 2

Ligand Name

2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine

DrugBank ID

None

PDB Ligand Accession

Z99

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

VLZBRVJVCCNPRJ-KPHUOKFYSA-N

SMILES

c1ccc2c(c1)C(c3ccccc3O2)CC(C4CC4C(=O)O)(C(=O)O)N

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

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Mol*

Structure: 7MTQ

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Color Legend

Unassigned regionsLigand / hetero atomse7mtqA1e7mtqA2e7mtqA3e7mtqA4e7mtqB1e7mtqB2e7mtqB3e7mtqB4

ECOD domains from experimental PDB structures interacting with ligand Z99

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
Q14416	n/a	Z99	7mtq	e7mtqA2	A:24-110,A:133-184,A:321-490
Q14416	n/a	Z99	7mtq	e7mtqA3	A:185-320
Q14416	n/a	Z99	7mtq	e7mtqB3	B:185-320
Q14416	n/a	Z99	7mtq	e7mtqB4	B:24-110,B:133-184,B:321-490
Q14416	n/a	Z99	8jcu	e8jcu21	2:22-110,2:132-184,2:321-490
Q14416	n/a	Z99	8jcu	e8jcu23	2:185-320
Q14416	n/a	Z99	8jcv	e8jcv21	2:185-488
Q14416	n/a	Z99	8jcv	e8jcv24	2:22-111,2:132-186
Q14416	n/a	Z99	8jcw	e8jcw22	2:24-186
Q14416	n/a	Z99	8jcw	e8jcw24	2:185-488
Q14416	n/a	Z99	8jcx	e8jcx23	2:24-111,2:132-186
Q14416	n/a	Z99	8jcx	e8jcx24	2:185-488
Q14416	n/a	Z99	8jcy	e8jcy23	2:24-110,2:132-186
Q14416	n/a	Z99	8jcy	e8jcy24	2:185-488
Q14416	n/a	Z99	8jcz	e8jcz23	2:185-320
Q14416	n/a	Z99	8jcz	e8jcz24	2:24-184,2:321-490