4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile

Q14654 — ATP-sensitive inward rectifier potassium channel 11 channel Kir6.2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB11633

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
Q14654	DB11633	QKM	nD1	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	IRK
Q14654	DB11633	QKM	nD2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	IRK_C

Show other predicted domains (16)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
6C3O	e6c3oA2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3oC1	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3oB2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3oD2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3oA1	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
	e6c3oC2	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
	e6c3oB1	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
	e6c3oD1	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
6C3P	e6c3pA1	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3pD2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3pB2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3pC1	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e6c3pA2	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
	e6c3pD1	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
	e6c3pB1	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan
	e6c3pC2	5054.1.1	Voltage-gated ion channels	Voltage-gated ion channels	Voltage-gated ion channels	Lig_chan

ECOD domains from experimental PDB structures interacting with ligand DB11633

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found