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5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine

Q15303 — Receptor tyrosine-protein kinase erbB-4

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12267

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
Q15303DB122676GYnD1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsRecep_L_domain
Q15303DB122676GYnD2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainFurin-like
Q15303DB122676GYnD3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsRecep_L_domain,GF_recep_IV
Q15303DB122676GYnD4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainGF_recep_IV
Q15303DB122676GYnD5206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
Show other predicted domains (52)
PDB IDDomain NameECOD IDX GroupH GroupT GroupF Group
2AHXe2ahxA4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2ahxB4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2ahxA3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2ahxB2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e2ahxA1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e2ahxA5389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e2ahxB3389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e2ahxB5389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
2R4Be2r4bA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e2r4bB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BBTe3bbtB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3bbtD1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BBWe3bbwB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3bbwA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3BCEe3bceA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3bceB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e3bceC1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3U2Pe3u2pA1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u2pA2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u2pA3389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
3U7Ue3u7uF1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uF2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uA4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uB4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uC3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uC4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uD4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uE4207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uA1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uB3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uD3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uE3207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u7uF4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uF3389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uC1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uC2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uA2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uA3389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uB1389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uB5389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uD2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uD5389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uE2389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u7uE5389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
3U9Ue3u9uE1207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u9uE2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u9uF2207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u9uF5207.1.1Single-stranded right-handed beta-helixLeucine-rich repeatsLeucine-rich repeatsLRR_1
e3u9uE3389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u9uE4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u9uF4389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP
e3u9uF3389.6.1EGF-likeGrowth factor receptor domainGrowth factor receptor domainIGFBP

ECOD domains from experimental PDB structures interacting with ligand DB12267

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
No experimental ECOD data found