Attributes
UniProt ID
Protein Name
Leukotriene C4 synthase synthase
Ligand Name
(1~{S},2~{S})-2-[5-[cyclopropylmethyl(naphthalen-1-yl)amino]-4-methoxy-pyrimidin-2-yl]carbonylcyclopropane-1-carboxylic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QYPOYXFLLPVCEL-ROUUACIJSA-N
SMILES
COc1c(cnc(n1)C(=O)C2CC2C(=O)O)N(CC3CC3)c4cccc5c4cccc5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6R7D
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Color Legend
Unassigned regionsLigand / hetero atomse6r7dA1e6r7dB1e6r7dC1e6r7dD1e6r7dE1e6r7dF1e6r7dG1e6r7dH1e6r7dI1e6r7dJ1e6r7dK1e6r7dL1
ECOD domains from experimental PDB structures interacting with ligand JUQ
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q16873 | n/a | JUQ | 6r7d | e6r7dA1 | A:-4-144 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dB1 | B:-4-144 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dC1 | C:-4-143 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dD1 | D:-4-145 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dE1 | E:-4-144 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dF1 | F:-4-145 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dG1 | G:-4-144 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dH1 | H:-4-146 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dI1 | I:-4-143 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dJ1 | J:-4-144 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dK1 | K:-4-145 |
| Q16873 | n/a | JUQ | 6r7d | e6r7dL1 | L:-4-143 |