Attributes
UniProt ID
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LTKHPMDRMUCUEB-IBGZPJMESA-N
SMILES
C#CCN(Cc1ccc2c(c1)C(=O)N=C(N2)N)c3ccc(cc3)C(=O)NC(CCC(=O)O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 1QZF
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Color Legend
Unassigned regionsLigand / hetero atomse1qzfA1e1qzfA2e1qzfB1e1qzfB2e1qzfC1e1qzfC2e1qzfD2e1qzfD3e1qzfE1e1qzfE2
ECOD domains from experimental PDB structures interacting with ligand DB03541