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ACETATE ION

Q27793 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB14511

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB14511

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q27793DB145113irmACTA803e3irmA1Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113irmACTA803e3irmA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q27793DB145113irmACTA803e3irmC2Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113irmACTB806e3irmB1Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113irmACTB806e3irmD2Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113irmACTB806e3irmD3Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q27793DB145113irmACTC807e3irmC3Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q27793DB145113irmACTD808e3irmD3Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q27793DB145113iroACTA809e3iroA1Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113iroACTA809e3iroC2Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113iroACTA809e3iroC3Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q27793DB145113iroACTB811e3iroB2Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113iroACTC813e3iroC2Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113iroACTD816e3iroB2Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt
Q27793DB145113iroACTD816e3iroB3Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q27793DB145113iroACTD816e3iroD1Thymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylate synthase/dCMP hydroxymethylaseThymidylat_synt