DrugDomain logoDrugDomain

(4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid

Q2TR58 — Beta-lactamase OXA-58

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand MER

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand MER

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q2TR58n/a7vviMERA302e7vviA1Profilin-likea+b domain in beta-lactamase/transpeptidase-like proteinsa+b domain in beta-lactamase/transpeptidase-like proteinsTranspeptidase
Q2TR58n/a7vviMERA302e7vviA2alpha-helical domain in beta-lactamase/transpeptidase-like proteinsalpha-helical domain in beta-lactamase/transpeptidase-like proteinsalpha-helical domain in beta-lactamase/transpeptidase-like proteinsTranspeptidase
Q2TR58n/a7vx3MERA302e7vx3A1Profilin-likea+b domain in beta-lactamase/transpeptidase-like proteinsa+b domain in beta-lactamase/transpeptidase-like proteinsTranspeptidase
Q2TR58n/a7vx3MERA302e7vx3A2alpha-helical domain in beta-lactamase/transpeptidase-like proteinsalpha-helical domain in beta-lactamase/transpeptidase-like proteinsalpha-helical domain in beta-lactamase/transpeptidase-like proteinsTranspeptidase
Q2TR58n/a7vx6MERA302e7vx6A1Profilin-likea+b domain in beta-lactamase/transpeptidase-like proteinsa+b domain in beta-lactamase/transpeptidase-like proteinsTranspeptidase
Q2TR58n/a7vx6MERA302e7vx6A2alpha-helical domain in beta-lactamase/transpeptidase-like proteinsalpha-helical domain in beta-lactamase/transpeptidase-like proteinsalpha-helical domain in beta-lactamase/transpeptidase-like proteinsTranspeptidase