RASAGILINE

Q2TW47 — NADPH-dependent reductive aminase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB01367

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB01367

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q2TW47	DB01367	5g6s	RAU	A	400	e5g6sA1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	A	400	e5g6sA2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	A	400	e5g6sG2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	B	400	e5g6sB1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	B	400	e5g6sB2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	B	400	e5g6sC1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	C	400	e5g6sB1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	C	400	e5g6sC1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	C	400	e5g6sC2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	D	400	e5g6sD1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	D	400	e5g6sD2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	D	400	e5g6sF1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	E	400	e5g6sE1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	E	400	e5g6sE2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	E	400	e5g6sH1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	F	400	e5g6sD2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	F	400	e5g6sF1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	F	400	e5g6sF2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	G	400	e5g6sA1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	G	400	e5g6sA2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	G	400	e5g6sG1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	G	400	e5g6sG2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	H	400	e5g6sE1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
Q2TW47	DB01367	5g6s	RAU	H	400	e5g6sE2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	H	400	e5g6sH1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
Q2TW47	DB01367	5g6s	RAU	H	400	e5g6sH2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2