DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Lanosterol 14-alpha-demethylase
Ligand Name
6-[(R)-(4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KVNUNQVIQXLHFU-MUUNZHRXSA-N
SMILES
Cn1cncc1C(c2ccc(cc2)Cl)(c3ccc4c(c3)C(=CC(=O)N4C)c5c(cccc5F)F)OC
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3TIK
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Color Legend
Unassigned regionsLigand / hetero atomse3tikA1e3tikB1e3tikC1e3tikD1
ECOD domains from experimental PDB structures interacting with ligand JKF
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q385E8n/aJKF3tike3tikA1A:28-477
Q385E8n/aJKF3tike3tikB1B:28-477
Q385E8n/aJKF3tike3tikC1C:28-477
Q385E8n/aJKF3tike3tikD1D:28-477