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(6S)-5,6,7,8-TETRAHYDROFOLATE

Q4DLS1 Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB02031

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB02031

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q4DLS1DB020315t7oTHGA702e5t7oA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q4DLS1DB020315t7oTHGB601e5t7oB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q4DLS1DB020315t7oTHGC601e5t7oC2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q4DLS1DB020315t7oTHGD703e5t7oD1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1