IRON/SULFUR CLUSTER

Q56220 — NADH-quinone oxidoreductase subunit 4

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand SF4

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand SF4

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q56220	n/a	2fug	SF4	6	182	e2fug41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	6	182	e2fug43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	F	182	e2fugD1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	F	182	e2fugD3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	O	182	e2fugM1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	O	182	e2fugM3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	X	182	e2fugV1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	2fug	SF4	X	182	e2fugV3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	2ybb	SF4	6	182	e2ybb41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	2ybb	SF4	6	182	e2ybb43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3i9v	SF4	6	182	e3i9v41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3i9v	SF4	6	182	e3i9v43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3i9v	SF4	F	182	e3i9vD4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3i9v	SF4	F	182	e3i9vD6	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3iam	SF4	6	182	e3iam44	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3iam	SF4	6	182	e3iam45	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3iam	SF4	F	182	e3iamD4	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3iam	SF4	F	182	e3iamD5	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	6	182	e3ias44	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	6	182	e3ias46	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	F	182	e3iasD4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	F	182	e3iasD6	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	O	182	e3iasM4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	O	182	e3iasM6	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	X	182	e3iasV4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3ias	SF4	X	182	e3iasV6	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3m9s	SF4	6	182	e3m9s44	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3m9s	SF4	6	182	e3m9s46	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	3m9s	SF4	F	182	e3m9sD4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	3m9s	SF4	F	182	e3m9sD6	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	4hea	SF4	6	201	e4hea41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	4hea	SF4	6	201	e4hea43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	4hea	SF4	G	201	e4heaE4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	4hea	SF4	G	201	e4heaE6	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6i0d	SF4	6	201	e6i0d41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6i0d	SF4	6	201	e6i0d43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6i0d	SF4	G	201	e6i0dE1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6i0d	SF4	G	201	e6i0dE3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6i1p	SF4	6	201	e6i1p41	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6i1p	SF4	6	201	e6i1p43	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6i1p	SF4	G	201	e6i1pE2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6i1p	SF4	G	201	e6i1pE3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6q8o	SF4	6	201	e6q8o41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6q8o	SF4	6	201	e6q8o43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6q8o	SF4	G	201	e6q8oE1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6q8o	SF4	G	201	e6q8oE2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6q8w	SF4	6	201	e6q8w41	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6q8w	SF4	6	201	e6q8w42	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6q8w	SF4	G	201	e6q8wE1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6q8w	SF4	G	201	e6q8wE3	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6q8x	SF4	6	201	e6q8x41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6q8x	SF4	6	201	e6q8x43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6q8x	SF4	G	201	e6q8xE1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6q8x	SF4	G	201	e6q8xE2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6y11	SF4	6	201	e6y1142	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6y11	SF4	6	201	e6y1143	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6y11	SF4	G	201	e6y11E1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6y11	SF4	G	201	e6y11E2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6ziy	SF4	6	201	e6ziy42	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6ziy	SF4	6	201	e6ziy43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa
Q56220	n/a	6zjl	SF4	6	201	e6zjl41	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	Complex1_49kDa
Q56220	n/a	6zjl	SF4	6	201	e6zjl43	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Complex1_49kDa