IRON/SULFUR CLUSTER

Q56223 — NADH-quinone oxidoreductase subunit 3

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand SF4

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand SF4

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q56223	n/a	2fug	SF4	3	786	e2fug36	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	2fug	SF4	3	786	e2fug38	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	2fug	SF4	C	786	e2fugC1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	2fug	SF4	C	786	e2fugC4	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	2fug	SF4	L	786	e2fugL4	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	2fug	SF4	L	786	e2fugL6	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	2fug	SF4	U	786	e2fugU4	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	2fug	SF4	U	786	e2fugU7	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	2ybb	SF4	3	786	e2ybb310	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	2ybb	SF4	3	786	e2ybb35	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3i9v	SF4	3	786	e3i9v35	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3i9v	SF4	3	786	e3i9v37	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3i9v	SF4	C	786	e3i9vC10	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3i9v	SF4	C	786	e3i9vC5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3iam	SF4	3	786	e3iam310	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3iam	SF4	3	786	e3iam35	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3iam	SF4	C	786	e3iamC10	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3iam	SF4	C	786	e3iamC5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3ias	SF4	3	786	e3ias310	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3ias	SF4	3	786	e3ias35	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3ias	SF4	C	786	e3iasC10	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3ias	SF4	C	786	e3iasC5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3ias	SF4	L	786	e3iasL10	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3ias	SF4	L	786	e3iasL5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3ias	SF4	U	786	e3iasU10	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3ias	SF4	U	786	e3iasU5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3m9s	SF4	3	786	e3m9s310	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3m9s	SF4	3	786	e3m9s35	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	3m9s	SF4	C	786	e3m9sC10	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	3m9s	SF4	C	786	e3m9sC5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	4hea	SF4	3	803	e4hea310	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	4hea	SF4	3	803	e4hea35	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	4hea	SF4	D	803	e4heaD5	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	4hea	SF4	D	803	e4heaD7	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6i0d	SF4	3	803	e6i0d34	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6i0d	SF4	3	803	e6i0d37	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6i0d	SF4	D	803	e6i0dD5	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6i0d	SF4	D	803	e6i0dD7	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6i1p	SF4	3	803	e6i1p32	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6i1p	SF4	3	803	e6i1p36	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6i1p	SF4	D	803	e6i1pD5	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6i1p	SF4	D	803	e6i1pD6	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8o	SF4	3	803	e6q8o33	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8o	SF4	3	803	e6q8o37	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6q8o	SF4	D	803	e6q8oD1	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8o	SF4	D	803	e6q8oD4	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6q8w	SF4	3	803	e6q8w31	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8w	SF4	3	803	e6q8w36	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6q8w	SF4	D	803	e6q8wD6	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6q8w	SF4	D	803	e6q8wD7	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8x	SF4	3	803	e6q8x31	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8x	SF4	3	803	e6q8x37	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6q8x	SF4	D	803	e6q8xD1	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6q8x	SF4	D	803	e6q8xD7	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6y11	SF4	3	803	e6y1132	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6y11	SF4	3	803	e6y1135	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6y11	SF4	D	803	e6y11D4	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6y11	SF4	D	803	e6y11D6	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6ziy	SF4	3	803	e6ziy31	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6ziy	SF4	3	803	e6ziy34	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6ziy	SF4	3	803	e6ziy37	cradle loop barrel	RIFT-related	double psi	Molydop_binding
Q56223	n/a	6zjl	SF4	3	803	e6zjl32	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6zjl	SF4	3	803	e6zjl35	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6zjn	SF4	3	803	e6zjn32	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a
Q56223	n/a	6zjn	SF4	3	803	e6zjn36	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6zjy	SF4	3	803	e6zjy32	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Formate dehydrogenase/DMSO reductase, domain 1	Molybdop_Fe4S4
Q56223	n/a	6zjy	SF4	3	803	e6zjy33	Rossmann-like	Formate dehydrogenase/DMSO reductase, domains 2 and 3	Formate dehydrogenase/DMSO reductase, domains 2 and 3	n/a