DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
DNA topoisomerase 4 subunit B
Ligand Name
7-[(3R)-3-aminopyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QGPKADBNRMWEQR-MRVPVSSYSA-N
SMILES
c1c2c(c(c(c1F)N3CCC(C3)N)Cl)N(C=C(C2=O)C(=O)O)C4CC4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3FOE
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Color Legend
Unassigned regionsLigand / hetero atomse3foeA2e3foeA4e3foeA5e3foeB1e3foeB3e3foeB5e3foeC1e3foeC2e3foeD1e3foeD2
ECOD domains from experimental PDB structures interacting with ligand NFX
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q59961n/aNFX3foee3foeC1C:419-540,C:583-636
Q59961n/aNFX3foee3foeD2D:419-540,D:583-636
Q59961n/aNFX3rade3radC1C:414-541,C:578-640
Q59961n/aNFX3rade3radD1D:415-541,D:578-640