Attributes
UniProt ID
Protein Name
NAD-dependent protein deacylase sirtuin-5, mitochondrial
Ligand Name
3-[[(2~{S},3~{a}~{R},5~{R},6~{R},6~{a}~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2-[[(5~{S})-6-[[(2~{S})-3-(1~{H}-indol-3-yl)-1-oxidanylidene-1-(propan-2-ylamino)propan-2-yl]amino]-6-oxidanylidene-5-(phenylmethoxycarbonylamino)hexyl]amino]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxathiol-2-yl]amino]propanoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YXTVLLWQDXVSFE-WDVUSYHVSA-N
SMILES
CC(C)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(CCCCNC3(OC4C(C(OC4S3)COP(=O)(O)OP(=O)(O)OCC5C(C(C(O5)n6cnc7c6ncnc7N)O)O)O)NCCC(=O)O)NC(=O)OCc8ccccc8
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6EO0
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Color Legend
Unassigned regionsLigand / hetero atomse6eo0A1e6eo0A2e6eo0B1e6eo0B2e6eo0C1e6eo0C2e6eo0D1e6eo0D2
ECOD domains from experimental PDB structures interacting with ligand BVT
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0A1 | A:25-146,A:208-298 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0A2 | A:147-207 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0B1 | B:147-207 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0B2 | B:24-146,B:208-298 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0C1 | C:25-146,C:208-298 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0C2 | C:147-207 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0D1 | D:24-146,D:208-298 |
| Q6DHI5 | n/a | BVT | 6eo0 | e6eo0D2 | D:147-207 |