DrugDomain logoDrugDomain

6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine

Q6FPH0 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 06U

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 06U

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q6FPH0n/a3ro906UA1e3ro9A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q6FPH0n/a3ro906UB1e3ro9B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1