DrugDomain logoDrugDomain

5-{3-[3-(1,3-benzodioxol-5-yl)-5-methoxyphenyl]prop-1-yn-1-yl}-6-ethylpyrimidine-2,4-diamine

Q6FPH0 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 14Q

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 14Q

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q6FPH0n/a4h9814QA302e4h98A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q6FPH0n/a4h9814QB302e4h98B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1