5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
Q6FPH0 — Dihydrofolate reductase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB07142
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB07142
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q6FPH0 | DB07142 | 3eel | 53T | A | 229 | e3eelA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q6FPH0 | DB07142 | 3eel | 53T | B | 229 | e3eelB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |