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Attributes

UniProt ID
Q6FPH0
Protein Name
Dihydrofolate reductase
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 3CSE
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Color Legend
Unassigned regionsLigand / hetero atomse3cseA1e3cseB1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q6FPH0DB02338NDP3csee3cseA1A:3-227
Q6FPH0DB02338NDP3csee3cseB1B:3-227
Q6FPH0DB02338NDP3eeje3eejA1A:3-227
Q6FPH0DB02338NDP3eeje3eejB1B:3-227
Q6FPH0DB02338NDP3eeke3eekA1A:3-227
Q6FPH0DB02338NDP3eeke3eekB1B:3-227
Q6FPH0DB02338NDP3eele3eelA1A:3-227
Q6FPH0DB02338NDP3eele3eelB1B:3-227
Q6FPH0DB02338NDP3eeme3eemA1A:3-227
Q6FPH0DB02338NDP3eeme3eemB1B:3-227
Q6FPH0DB02338NDP3qlxe3qlxA1A:3-227
Q6FPH0DB02338NDP3qlxe3qlxB1B:3-227
Q6FPH0DB02338NDP3qlye3qlyA1A:3-227
Q6FPH0DB02338NDP3qlye3qlyB1B:3-227
Q6FPH0DB02338NDP3qlze3qlzA1A:3-227
Q6FPH0DB02338NDP3qlze3qlzB1B:3-227
Q6FPH0DB02338NDP3ro9e3ro9A1A:3-227
Q6FPH0DB02338NDP3ro9e3ro9B1B:3-227
Q6FPH0DB02338NDP3roae3roaA1A:3-227
Q6FPH0DB02338NDP3roae3roaB1B:3-227
Q6FPH0DB02338NDP4h98e4h98A1A:4-227
Q6FPH0DB02338NDP4h98e4h98B1B:4-227
Q6FPH0DB02338NDP4hoge4hogA1A:3-227
Q6FPH0DB02338NDP4hoge4hogB1B:3-227