BIS-(MU-2-OXO),[(MU-3--SULFIDO)-BIS(MU-2--SULFIDO)-TRIS(CYS-S)-TRI-IRON] (AQUA)(GLU-O)IRON(II)

Q72AS3 — Periplasmic hydrogenase, large subunit, selenocysteine-containing

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand FSX

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand FSX

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q72AS3	n/a	2wpn	FSX	A	1287	e2wpnB2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
Q72AS3	n/a	2wpn	FSX	A	1287	e2wpnB4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
Q72AS3	n/a	3ze6	FSX	A	287	e3ze6B2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
Q72AS3	n/a	3ze6	FSX	A	287	e3ze6B3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
Q72AS3	n/a	3ze6	FSX	A	287	e3ze6B4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
Q72AS3	n/a	3ze9	FSX	A	286	e3ze9B2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
Q72AS3	n/a	3ze9	FSX	A	286	e3ze9B3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
Q72AS3	n/a	3ze9	FSX	A	286	e3ze9B4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases