Attributes
UniProt ID
Protein Name
Isocitrate/homoisocitrate dehydrogenase
Ligand Name
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BOPGDPNILDQYTO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4YB4
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Color Legend
Unassigned regionsLigand / hetero atomse4yb4A1e4yb4A2e4yb4B1e4yb4B2e4yb4C1e4yb4C2e4yb4D1e4yb4D2
ECOD domains from experimental PDB structures interacting with ligand DB00157
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4A1 | A:2-94,A:240-334 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4A2 | A:95-239 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4B1 | B:2-94,B:240-334 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4B2 | B:95-239 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4C1 | C:2-94,C:240-334 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4C2 | C:95-239 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4D1 | D:2-94,D:240-334 |
| Q72IW9 | DB00157 | NAI | 4yb4 | e4yb4D2 | D:95-239 |