(2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane

Q7NDN8 — Proton-gated ion channel

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DSF

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DSF

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q7NDN8	n/a	3p4w	DSF	A	319	e3p4wA1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
Q7NDN8	n/a	3p4w	DSF	A	319	e3p4wA2	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
Q7NDN8	n/a	3p4w	DSF	B	319	e3p4wB1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
Q7NDN8	n/a	3p4w	DSF	B	319	e3p4wB2	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
Q7NDN8	n/a	3p4w	DSF	C	320	e3p4wC1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
Q7NDN8	n/a	3p4w	DSF	C	320	e3p4wC2	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
Q7NDN8	n/a	3p4w	DSF	D	319	e3p4wD1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
Q7NDN8	n/a	3p4w	DSF	D	319	e3p4wD2	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
Q7NDN8	n/a	3p4w	DSF	E	319	e3p4wE1	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
Q7NDN8	n/a	3p4w	DSF	E	319	e3p4wE2	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb