DrugDomain logoDrugDomain

(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(propan-2-yl)phthalazin-2(1H)-yl]prop-2-en -1-one

Q81R22 — Dihydrofolate reductase

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Attributes

UniProt ID
Q81R22
Protein Name
Dihydrofolate reductase
Ligand Name
(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(propan-2-yl)phthalazin-2(1H)-yl]prop-2-en -1-one
DrugBank ID
None
PDB Ligand Accession
31I
ChEMBL ID
None
PubChem ID
78225950
InChIKey
QGKBSLZXGYTSQX-GTCGAKFVSA-N
SMILES
CC(C)C1c2ccccc2C=NN1C(=O)C=Cc3cc(cc(c3OC)OC)Cc4cnc(nc4N)N
Drug Action
No data available
Affinity Metrics
No affinity data available