DrugDomain logoDrugDomain

(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(propan-2-yl)phthalazin-2(1H)-yl]prop-2-en -1-one

Q81R22 Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 31I

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 31I

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q81R22n/a4ele31IA203e4eleA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31IB203e4eleB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31IC203e4eleC1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31ID203e4eleD1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31IE203e4eleE1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31IF203e4eleF1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31IG203e4eleG1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q81R22n/a4ele31IH201e4eleH1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1