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Attributes

UniProt ID
Protein Name
Dihydrofolate reductase
Ligand Name
6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LBQMRSNKEUNXMT-UHFFFAOYSA-N
SMILES
CCc1c(c(nc(n1)N)N)C#CCc2cc(ccc2OC)c3ccccc3
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3S9U
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Color Legend
Unassigned regionsLigand / hetero atomse3s9uA1e3s9uB1
ECOD domains from experimental PDB structures interacting with ligand 5DR
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q81R22n/a5DR3s9ue3s9uA1A:-2-162
Q81R22n/a5DR3s9ue3s9uB1B:1-162