DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Dihydrofolate reductase
Ligand Name
6-ethyl-5-[3-(5-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QKLZHVMWTSBUFL-UHFFFAOYSA-N
SMILES
CCc1c(c(nc(n1)N)N)C#CCc2cc(cc(c2)OC)c3ccccc3
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3SA2
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Color Legend
Unassigned regionsLigand / hetero atomse3sa2A1e3sa2B1
ECOD domains from experimental PDB structures interacting with ligand 7DR
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q81R22n/a7DR3sa2e3sa2A1A:1-162
Q81R22n/a7DR3sa2e3sa2B1B:1-162